| Item Type | Name |
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Concept
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Cell Proliferation
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Academic Article
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Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells.
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Academic Article
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A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin.
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Academic Article
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c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention.
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Academic Article
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Protein kinase C beta in malignant pleural mesothelioma.
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Academic Article
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Fyn: a novel molecular target in cancer.
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Academic Article
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Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer.
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Academic Article
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Effect of a c-Met-specific, ATP-competitive small-molecule inhibitor SU11274 on human ovarian carcinoma cell growth, motility, and invasion.
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Academic Article
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A novel classification of lung cancer into molecular subtypes.
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Academic Article
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Sphingosine kinase 1 is required for mesothelioma cell proliferation: role of histone acetylation.
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Academic Article
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Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion.
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Academic Article
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NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases.
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Academic Article
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An E3 ubiquitin ligase: c-Cbl: a new therapeutic target of lung cancer.
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Academic Article
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The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.
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Academic Article
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The Mu opioid receptor promotes opioid and growth factor-induced proliferation, migration and Epithelial Mesenchymal Transition (EMT) in human lung cancer.
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Academic Article
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MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma.
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Academic Article
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Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.
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Academic Article
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Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancer.
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Academic Article
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Dramatic antitumor effects of the dual MET/RON small-molecule inhibitor LY2801653 in non-small cell lung cancer.
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Academic Article
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Overcoming acquired resistance to cetuximab by dual targeting HER family receptors with antibody-based therapy.
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Academic Article
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Nuclear epidermal growth factor receptor is a functional molecular target in triple-negative breast cancer.
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Academic Article
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Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer.
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Academic Article
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Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.
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Academic Article
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Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
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Academic Article
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Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.
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Academic Article
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Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab.
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Academic Article
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PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma.
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Academic Article
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TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
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Academic Article
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MET in Lung Cancer: Biomarker Selection Based on Scientific Rationale.
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Academic Article
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Loss of H2B monoubiquitination is associated with poor-differentiation and enhanced malignancy of lung adenocarcinoma.
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Academic Article
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Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer.
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Academic Article
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SOX9: The master regulator of cell fate in breast cancer.
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Academic Article
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Effects of selected deubiquitinating enzyme inhibitors on the proliferation and motility of lung cancer and mesothelioma cell lines.
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Academic Article
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Therapeutic targeting of miRNA-216b in cancer.
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Academic Article
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Targeting RLIP with CRISPR/Cas9 controls tumor growth.
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Academic Article
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Lysocardiolipin acyltransferase regulates NSCLC cell proliferation and migration by modulating mitochondrial dynamics.
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Academic Article
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MicroRNA-1: Diverse role of a small player in multiple cancers.
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Academic Article
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Protein Phosphatase 2A as a Therapeutic Target in Small Cell Lung Cancer.
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Academic Article
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MicroRNA-1 attenuates the growth and metastasis of small cell lung cancer through CXCR4/FOXM1/RRM2 axis.
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Grant
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Role of c-Met in SCLC and Potential for Novel Therapy
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Grant
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Studies of a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC)
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